Alpha1Health.com | Testing Information for the Alpha-1 Community | ARALAST Safety

ARALAST Safety

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ARALAST [Alpha1-Proteinase Inhibitor (Human)] is prepared from human plasma using the Cohn-Oncley cold alcohol fractionation process.

ARALAST has a multi-step purification process that includes two viral treatment steps:

  • Solvent Detergent Treatment rapidly inactivates lipid-enveloped viruses such as HIV and Hepatitis B and C.
  • Nanofiltration reduces the risk of transmission of non-lipid-enveloped viral agents such as Hepatitis A and Parvovirus B19.
Aralast Creation

As with all plasma-derived therapeutics, the potential to transmit infectious agents cannot be totally eliminated.

ARALAST [Alpha1-Proteinase Inhibitor (Human)] is indicated for chronic augmentation therapy in patients having congenital deficiency of A1-PI with clinically evident emphysema. ARALAST is not indicated as therapy for lung disease patients in whom congenital A1-PI deficiency has not been established.

Please review the Important Safety Information and the Full Prescribing Information

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